What were the top 100 research antibodies of 2022?


Min Read

In this blog:

  • Which antibody suppliers are leading with the most highly cited products of the year?
  • What trends can we see for the types of products used by researchers?
  • Download the complete list of the top 100 cited antibodies in 2022

Welcome to the top 100 product series in 2023! 

Interested in what the most cited research antibodies were in the past year? Searching for information on the suppliers with highly competitive products in the antibody market? Looking for insight to help inform your antibody product pipeline decisions?

Look no further – today we take you through our analysis of the top 100 cited products in the research antibody market in 2022.

You are also able to download the antibody market data freely at the bottom of this blog.

What data was used in this analysis? 

Our complete antibody database covers nearly 8 million antibodies and over 4 million citations from more than 300 suppliers, with this number constantly growing. 

To bring you this blog we delve into a section of our complete research antibody database. Our analysis today incorporates preprint citations, as well as citations from open and closed-access journals to produce a more accurate view of the top 100 products used by scientists. 

To create our antibody market dataset, we text-mine the scientific literature to generate highly-accurate, structured citation data, enabling us to understand, quantitatively, how products have been used in research. This data can give insight into companies to watch, broader market trends, and even granular trends within research areas, institutions and applications. You can read more about our market data here.

Today, we use it to shed light into the most highly cited products. Here’s what we found…

Which antibody suppliers had the most highly cited antibodies of the year?

Cell Signaling Technology have maintained their position as the supplier with the most highly cited antibodies featured in the top 100. We found that 36 out of the top 100 cited antibodies were supplied by CST. The number of products in the top 100 from CST has also increased by one since our analysis carried out in 2022.

Abcam and Thermo Fisher Scientific round off the top 3 suppliers in this list. Abcam, the second most featured supplier, claims a significant 18 of the top 100 products. Thermo Fisher Scientific holds 17 of the top 100 most cited antibodies, increasing their count by one product since last year. MilliporeSigma follow closely behind with 13 products in the top 100.

Pie chart to show the antibody suppliers featured in the top 100 dataset and their share of products
Pie chart to show the antibody suppliers and their share of products featured in the top 100 dataset

Although we see a similar spread of suppliers in this dataset to previous analysis, this year we have seen fluctuations in the number of products featured for many suppliers – going to show the market is far from static. We will be interested to see if these fluctuations result in any shifts in the rankings or more significant changes to the dataset in future years.

So, which suppliers and products in particular should you be paying attention to?

Antibody suppliers and products to watch

Our analysis revealed a new supplier’s entry into the top 100 for the first time, and notable growth for another company. 

Antibody vendors to watch

Beyotime Biotechnology entered the top 100 list for the first time, with their HRP-labeled Goat Anti-Rabbit IgG(H+L) (cat# A0208) in 75th. They were the only antibody vendor to break into the top 100 list this year, with 12 suppliers featuring overall. We’ve noticed that over the past three years, we’ve seen a new supplier each year break into the top 100.

We also found that Proteintech have continued their positive growth trajectory, increasing the number of antibodies that appear in this list as most cited by researchers. Last year they added two antibodies to the top 100 and this year they added another one, bringing their total to 5. This has meant they have now overtaken Santa Cruz Biotechnology to become the 5th most featured supplier in the top 100 dataset.

Other suppliers we have noticed include Jackson ImmunoResearch, the 7th most featured supplier in the dataset. Despite their main focus on secondary antibodies, they have maintained their inclusion in this broader list with two Peroxidase-AffiniPure Goat Anti-Rabbit IgG (H+L)products featured.

Find out more about antibody market data options we offer

Antibody products to watch

Turning our attention to products to watch, we found that the top 10 cited antibodies have stayed broadly consistent with last year’s dataset. There was, however, one newcomer to the top 10: Cell Signaling Technology’s Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP Rabbit mAb (Cat#4370). Its break into the top has replaced GAPDH (14C10) Rabbit mAb (Cat# 2118). 

Outside of the top 10, we saw 6 new antibodies enter the top 100 list this year. These antibodies were :

  • Proteintech’s Beta actin monoclonal antibody (cat# 66009-1-Ig) in 52nd
  • Beyotime Biotechnology’s HRP-labeled Goat Anti-Rabbit IgG(H+L) (cat# A0208) in 75th
  • CST’s Phospho-Histone H2A.X (Ser139) (20E3) Rabbit mAb (cat# 9718) in 76th
  • Thermo’s Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 647 (cat# A-31571) in 91st
  • CST’s Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb (cat# 4668) in 92nd
  • Abcam’s Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (cat# ab150113) in 97th

These products interestingly reflect a spread in suppliers, targets and primary and secondary antibodies. There may be a number of reasons these antibodies have entered the list: effective product portfolio curation, increased marketing or an uptick in certain research needs to name but a few.

Types of antibodies featuring in the top 100

When we looked into the top 100 products by antibody type, we noticed some trends. 

The number of recombinant antibodies in the data has increased from last year, with this antibody type now making up a quarter of the list. This is to be expected, mirroring the trend of more recombinants being used in research.

We also found that the majority of antibodies featured were primary, with only 30 secondary antibodies making the list. This remains fairly similar to what we discovered in data from last year. 

Despite the fact only 30 secondary antibodies were included in this list, they claim the two top spots. The most cited antibody of 2022 was Cell Signaling Technology’s Anti-rabbit IgG, HRP-linked Antibody (Cat# 7074). In fact, this antibody has held the top sport for the last 6 years, showing it continues to be a valuable tool in the eyes of researchers. Another HRP-linked antibody from CST – their Anti-mouse IgG, HRP-linked Antibody (Cat# 7076) – has also seen growing research interest in the past year, moving up to claim the 2nd most cited spot. 

We will be interested to see how this data changes over the course of the next year; we will be keeping an eye on trends, suppliers and products of interest from this dataset. 

Download the dataset

By simply signing up below you can download the full list of the top 100 antibodies of 2022, so that you can perform your own analysis on the data.

Our antibody data can be an invaluable asset when selecting products to raise for your portfolio, helping reduce the risks involved in developing new and commercially successful antibodies.

If you’re interested in further antibody data, or data covering other reagents, get in touch with the team!  We’re more than happy to answer any questions you have on our life science market data and chat about the ways it can help your business.

We’ll be sharing similar analysis on other reagent types (covering cell lines, biochemicals, proteins, and kits)  over the next couple of months, so do check back on our blog to learn more about the top products in different markets.

  • Rhys and the CiteAb team

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